Brain cancer breakthrough as scientists find 'window' to attack tumours after surgery

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Scientists have discovered a brain cancer breakthrough after finding a "window" to attack tumours after surgery.A landmark study from The University of Manchester, published today in Science Translational Medicine, has revealed that chemotherapy could prove far more potent against glioblastoma if delivered during two brief post-operative windows rather than after the conventional weeks-long wait.The research team discovered that the blood-brain barrier — a protective cellular layer that ordinarily blocks drugs from reaching the brain — becomes temporarily permeable at two distinct points following tumour removal surgery.These critical openings occur at 15 minutes and between 48 and 72 hours after the operation, offering fleeting but potentially transformative opportunities to attack residual cancer cells.

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